Biden experiences a Covid rebound after treatment with one course of Paxlovid

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President Joe Biden gives remarks during a meeting on the U.S. Economy with CEOs and members of his Cabinet in the South Court Auditorium of the White House on July 28, 2022 in Washington, DC. | Anna Moneymaker/Getty Images

President Biden tested positive for Covid-19 late Saturday morning, the White House physician said, and he is not experiencing any symptoms at this time.

“The President has no experienced any reemergency of symptoms and is feeling quite well,” White House physician Kevin O’Connor wrote in a memo released Saturday. “This being the case, there is no reason to reinitiate treatment at this time, but we will obviously continue close observation.”

He will now need to isolate for another five days. Biden’s returning symptoms are an example of a rebound Covid-19 case, a phenomenon that has happened in some cases after people take Paxlovid.

Biden experienced mild symptoms in the upper floors of the White House after he tested positive for Covid-19 a week ago Thursday. He completed an initial five-day course of Paxlovid, an antiviral therapy from Pfizer, on Monday, and on Tuesday evening and Wednesday morning, the president tested negative for Covid-19 and ended isolation.

In late May, the Centers for Disease Control and Prevention issued a health advisory about the recurrence of symptoms and noted that there have been no cases of severe disease as part of this rebound. The agency also said that there is currently no evidence that a second round of Paxlovid is necessary for these symptoms to resolve.

However, that hasn’t stopped some physicians from prescribing patients a second round of Paxlovid out of an abundance of caution. Anthony Fauci, the White House chief medical adviser, received two courses of the antiviral after experiencing a similar rebound of symptoms.

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